CHROMOSOMAL DEFECTS AND OMPHALOCELE (1-20)  

 

 

Reference

Number
of cases

GA(wks)

Chromosomal Defects

Total %

Trisomy 18

Trisomy 13

Other

(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
(19)
(20)

10
12
35
10
46
30
26
22
10
12
22
24
22
37
18
116
13
16
18

11-37
19-25
16-36
15-40
15-36
12-40
12-30
14-28
12-41
15-38
15-34
12-40
12-38
16-40
11-38
16-39
13-39
14-24
11-14
10-14

10%
66%
54%
40%
26%
43%
38%
18%
50%
58%
23%
29%
45%
14%
39%
36%
23%
31%
67%

1
7
17
2
6
4
4
1
3
5
3
5
6
3
3
32
3
3
10
9

-
-
-
1
2
5
4
2
1
2
1
1
1
1
-
7
-
-
1
1

-
1
2
1
4
4
2
1
1
-
1
1
3
1
4
3
-
2
1
8

 

 

 

REFERENCES

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  2. Nicolaides KH, Rodeck CH, Godsen CM. Rapid karyotyping in non-lethal fetal malformations. Lancet 1986;1:283-287.
  3. Gilbert WM, Nicholaides KH. Fetal omphalocele: associated malformations and chromosomal defects. Obstet Gynecol 1987;70:633-635.
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  11. Getachew MM, Goldstein RB, Edge V et.al Correlation between omphalocele contents and karyotypic abnormalities: Sonographic study in 37 cases. Am J Roentgenol 1991;158:133-136.
  12. Rezai, K., Holzgreven, W., Schloo, R. et.al. Chromosomenbefunde bei sonographisch auffalligen Feten. Geburtsch Frauenheilk 1991;51:211-116.
  13. Van de Geijn, E.J., Van Vugt, J.M.G., Sollie, J.E. et.al. Ultrasonographic diagnosis and perinatal management of fetal abdominal wall defects. Fetl Diagn Ther 1991;6:2-10.
  14. Fogel, M., Copel, J.A., Cullen, M.T., et.al.; Congenital heart disease and fetal thoracoabdominal anomalies: association in utero and the importance of cytogenetic analysis Am J Perinatol 1991;8:411-416.
  15. Van Zalen-Sprockm, M.M., Van Vugt, J.M.G., Karsdorp, V.H.M. et.al Ultrasound diagnosis of fetal abnormalities and cytogenetic evaluation. Prenat Diagn 1991;11:655-660.
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  18. Morrow, R.J., Whittle, J.J., McNay, M.B. et.al. Prenatal diagnosis and management of anterior abdominal wall defects in the west of Scotland. Prenat Diagn 1993;13:111-115.
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